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Scientists have developed a new class of antibiotics to treat drug-resistant bacteria that cause deadly infections in humans. The novel antibiotic, Zosurabalpin, shows promising results in treating highly drug-resistant strains of Carbapenem-resistant Acinetobacter baumannii (CRAB) in mouse models, according to the study published in Journal Nature. The research was conducted by Roche Pharma Research and
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TOPLINE: Novel fusion protein telitacicept showed safety and effectiveness in patients with systemic lupus erythematosus (SLE) in an early stage randomized trial. METHODOLOGY: The researchers recruited 249 adults with SLE from 29 hospitals in China; participants were randomized into four groups to receive telitacicept subcutaneously at a dose of 80 mg, 160 mg, or 240
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There’s no question that glucagon-like peptide 1 (GLP-1) agonists represent a major advance in the treatment of obesity for patients with or without diabetes. In clinical trials, participants lost 15%-20% of their body weight, depending on the drug. But studies also have shown that once people stop taking these drugs — either by choice, because
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The relationship between lipid levels and the development of dementia is an evolving but confusing landscape. “This is an incredibly complex area, and there really isn’t a clear consensus on this subject because different lipid classes reflect different things,” according to Betsy Mills, PhD, Assistant Director of Aging and Alzheimer’s Prevention at the Alzheimer’s Drug
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TOPLINE: Transcranial alternating current stimulation (tACS), a noninvasive technique that uses low-intensity electrical currents to modulate brain activity, is an effective intervention for treating chronic insomnia, especially in older people, results of a relatively large study suggested. METHODOLOGY: The double-blind study included 124 adults with chronic insomnia (difficulty falling asleep or maintaining sleep and early
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Maternal mortality rates in the UK have reached levels not witnessed since 2003-05. According to a collaborative investigation led by MBRRACE-UK (Mothers and Babies: Reducing Risk Through Audits and Confidential Enquiries), the maternal death rate during or shortly after pregnancy stood at 13.41 deaths per 100,000 maternities (95% CI, 11.86-15.10) in the period 2020-22. This
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Medicare will now cover the use of an AI-based test for prostate cancer that can predict which men will benefit from potentially disabling androgen deprivation therapy. The Centers for Medicare & Medicare Services (CMS) on January 1 approved the payment rate for ArteraAI as a clinical diagnostic laboratory test. The test is the first that
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Xanomeline-trospium (KarXT) — a novel therapy that combines a muscarinic receptor agonist with an anticholinergic agent — led to statistically significant and clinically meaningful improvements in positive and negative symptoms of schizophrenia compared with placebo in the phase 3 EMERGENT-2 trial, a new study shows. Xanomeline-trospium treatment was not associated with weight gain compared with
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